MICROCIRCULATORY DISTURBANCES IN PATIENTS WITH POST-COVID SYNDROME AND TROPHIC ULCERS OF THE MUCOSUS MEMBRANE OF THE ORAL CAVITY

Received: 2023-01-24 16:51:54

Published: 2023-01-25

Abstract

The Covid 19 pandemic, which has affected more than 400 million people worldwide, about 20-30% of patients, does not fully recover and continues to experience post-COVID syndrome (PCS). One of these symptoms is the appearance of trophic ulcers on the oral mucosa (OM). One of the likely mechanisms for the development of trophic ulcers in the oral cavity is a violation of the microcirculation of blood and lymphatic vessels. An important non-invasive method for diagnosing the state of capillary blood flow in trophic ulcers of the oral mucosa in patients with a history of Covid 19 is the determination of the microcirculation of tissue vessels.

List of references

  1. Иноятов А.Ш., Саидова Н.А., Саидова М.А. КЛИНИЧЕСКОЕ ТЕЧЕНИЕ ТРОФИЧЕСКИХ ЯЗВ СЛИЗИСТОЙ ОБОЛОЧКИ ПОЛОСТИ РТА У ПОСТКОВИДНЫХ ПАЦИЕНТОВ. НОВЫЙ ДЕНЬ В МЕДИЦИНЫ 12(50)2022: 326-330.

  2. Камилов Х.П., Ибрагимова М.Х. //Биохимические показатели крови и слюны у больных с патологией гепатобилиарной системы. //Научно-практический журнал STOMATOLOGIYA. Ташкент, 2018. – № 3. - С. 79-82

  3. Камилов Х. П., Ибрагимова М.Х., Камилова А.З. К вопросу этиопатогенеза, клиники, диагностики и лечения больных с глоссалгией, перенесших Covid19 на этапе реабилитации. //Journal of medicine and innovations» №2,2021.P 77-80.

  4. Камилов Х.П, Ибрагимова М.Х, Убайдуллаева Н.И. Современный взгляд на этиопатогенез, диагностику и лечение хронического рецидивирующего афтозного стоматита при хроническом холецистите. //Journal of medicine and innovations»,2021. P 80-86

  5. Сидоров В.В. и др. Нарушения микроциркуляции и клеточного метаболизма у пациентов, с постковидным синдромом // Вестник новых медицинских технологий. 2022. Т. 29, № 2. С. 64–68;

  6. Avila J, Long B, Holladay D, Gottlieb M.Thrombotic complications of COVID-19. Am J Emerg Med. 2021 Jan;39:213-218. doi: 10.1016/j.ajem.2020.09.065. Epub 2020 Oct 1.PMID: 33036855 Free PMC article. Review.

  7. COVID-19 / epositorium of COVID-19 data of the Center for System Sciences and Engineering (CSSE) [Electronic resource] // Johns Hopkins University.

  8. Das S. Microcirculatory changes and thrombotic complications in COVID-19 // British Journal of Community Nursing. 2021. Vol. 26,Iss. 10. P. 474–480.

  9. Hsu A, Ohnigian S, Chang A, Liu Y, Zayac AS, Olszewski AJ, Reagan JL.Thrombosis in COVID-19: A Narrative Review of Current Literature and Inpatient Management.

  10. R I Med J (2013). 2021 Jun 1;104(5):14-19.PMID: 34044431 Review.

  11. Jenner WJ, Kanji R, Mirsadraee S, Gue YX, Price S, Prasad S, Gorog DA. Thrombotic complications in 2928 patients with COVID-19 treated in intensive care: a systematic review. J Thromb Thrombolysis. 2021 Apr;51(3):595-607. doi: 10.1007/s11239-021-02394-7. Epub 2021 Feb 14.PMID: 33586113 Free PMC article.

  12. Manolis AS, Manolis TA, Manolis AA, Papatheou D, Melita H.COVID-19 Infection: Viral Macro- and Micro-Vascular Coagulopathy and Thromboembolism /Prophylactic and Therapeutic Management.J Cardiovasc Pharmacol Ther. 2021 Jan;26(1):12-24. doi: 10.1177/1074248420958973. Epub 2020 Sep 14.PMID: 32924567 Free PMC article.

  13. Pandolfi S., Chirumbolo S. Home therapy of COVID-19 at the earliest may greatly prevent hospitalization // Basik and Clinical Pharmacology and Toxicology. 2021. Vol. 129, Iss. 6. P. 395–396.

  14. Sidorov V.V. A device for comprehensive noninvasive diagnostics of the tissue microcirculation system of human skin / Sidorov V.V. [et al.] // Biomedical Engineering. 2021. Vol. 55, No. 4. P. 232–235

  15. Rovas А., Kümpers Ph. Störung der Mikrozirkulation bei

  16. COVID-19 // Medizinische Klinik - Intensivmedizin und Notfallmedizin.

  17. Vol. 116. P. 530–534 / Rovas А, Kümpers Ph. Störung der Mikrozirkulation bei COVID-19. Medizinische Klinik - Intensivmedizin und Notfallmedizin. 2021;116:530-4.

About the Authors

Inoyatov Amrillo Shodiyevich
Minister of Health of the Republic of Uzbekistan, Doctor of Medicine, Professor, Tashkent, Uzbekistan
https://orcid.org/0000-0001-7679-1695 (unauthenticated)
Saidova Mukhlisa Akhrorovna
Tashkent State Dental Institute, PhD student, Tashkent, Uzbekistan
https://orcid.org/0000-0003-1803-6194 (unauthenticated)

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How to Cite

1.
MICROCIRCULATORY DISTURBANCES IN PATIENTS WITH POST-COVID SYNDROME AND TROPHIC ULCERS OF THE MUCOSUS MEMBRANE OF THE ORAL CAVITY. MSU [Internet]. 2023 Jan. 25 [cited 2026 Mar. 2];(1):06-8. Available from: https://fdoctors.uz/index.php/journal/article/view/19

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