HEMODYNAMICS OF THE KIDNEY IN CHILDREN WITH OBESITY
Abstract
Abstract: the original article presents the results of a study of the relationship between impaired renal function and microalbuminuria as a manifestation of complications in obesity in children. The results of the study are recommended for implementation in the practice of endocrinologists, pediatricians and nephrologists. Objective of the study: to study the functional state of the kidneys based on Doppler ultrasound in relation to the level of microalbuminuria. 40 children with obesity aged 5 to 18 years were examined, 20 children with normal body weight for their age formed the control group. Results of the study: a relationship was found between the pathology of carbohydrate and lipid status and the level of microalbuminuria. The data are presented, characterized by the violation of renal hemodynamics at the level of interlobar and arcuate renal arteries in children with obesity and severe microalbuminuria. Conclusion: a decrease in the rate of hemodynamics at the level of large renal vessels allows us to consider them as a marker of early disorders of renal hemodynamics.
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List of references
Okunogbe et al., “Economic Impacts of Overweight and Obesity.” 2nd Edition with Estimates for 161 Countries. World Obesity Federation, 2022.
Hannon, T.S.; Arslanian, S.A. Obesity in adolescents. N. Engl. J. Med. 2023,389, 251–261.
Barlabà, A.; Grella, C.; Tammaro, M.; Petrone, D.; Guarino, S.; Miraglia Del Giudice, E.; Marzuillo, P.; Di Sessa, A. Kidney function evaluation in children and adolescents with obesity: A not-negligible need. Eur. J. Pediatr. 2024,183, 3655–3664.
Carullo, N.; Zicarelli, M.; Michael, A.; Faga, T.; Battaglia, Y.; Pisani, A.; Perticone, M.; Costa, D.; Ielapi, N.; Coppolino, G.; et al. Childhood Obesity: Insight into kidney involvement. Int. J. Mol. Sci. 2023,24, 17400.
Sawyer, A.; Zeitler, E.; Trachtman, H.; Bjornstad, P. Kidney considerations in pediatric obesity. Curr. Obes. Rep. 2023,12, 332–344.
Hales, C.M.; Carroll, M.D.; Fryar, C.D.; Ogden, C.L. Prevalence of Obesity and Severe Obesity Among Adults: United States, 2017–2018; NCHS Data Brief; CDC National Center for Health Statistics: Hyattsville, MD, USA, 2020; pp. 1–8.
Kopple, J.D. Obesity and chronic kidney disease. J. Ren. Nutr. 2010,20 (Suppl. S5), S29–S30,
Vyalkova AA, Lebedeva EN, Krasikov SI, et al. Clinical and pathogenetic aspects of kidney damage in obesity (literature review). Nephrology 2014; (3): 24–289. Di Sessa, A.; Guarino, S.; Umano, G.R.; Miraglia Del Giudice, E.; Marzuillo, P. MASLD vs. NAFLD: A better definition for children with obesity at higher risk of kidney damage. J. Hepatol. 2024,80, e87–e89.
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