MICROALBUMINURIA IN CHILDREN WITH METABOLIC SYNDROME

Abstract

Resume: This article presents data on urinary albumin excretion in obese children. The study results are recommended for widespread implementation by general practitioners in central district primary care clinics. Objective: To assess renal function by determining microalbuminuria levels. Materials and Methods: A total of 200 children with exogenous-constitutional obesity, divided into groups with abdominal and uniform fat distribution, were examined, along with 98 children with normal body weight. A combination of anthropometric, biochemical, and enzyme immunoassay studies was conducted, and urinary albumin excretion levels were determined. Study results: The obtained results characterize microalbuminuria as a predictor of the development of metabolic syndrome in abdominal obesity, starting in children aged 7-9 years, with a tendency for pathological levels to increase at ages 16-18 years. A pronounced albumin excretion was noted in boys with abdominal obesity, as well as a clear correlation between the increase in urinary albumin and the degree of obesity. Conclusions: All children with abdominal obesity, regardless of the number of metabolic syndrome components, had pathological microalbuminuria, which characterizes microalbuminuria as a predictor of the development of complications associated with abdominal obesity, which worsen depending on the severity of metabolic pathology.