PATHOMORPHOLOGY OF CHANGES IN ALVEOLAR STRUCTURES OF THE LUNGS IN PNEUMOPATHIES AT DIFFERENT PERIODS OF GESTATION
Received: 2025-04-05 11:09:59
Published: 2025-04-16
Abstract
Pathomorphological changes in the alveolar structures of the lungs of fetuses and newborn infants who died from various forms of pneumopathy were noted at 22-28 weeks of gestation: total atelectasis, diapedetic hemorrhages, desquamation of the mucous epithelium of the bronchioles, at 29-31 and 32-36 weeks of gestation: small scattered primary atelectasis, hyaline membranes, edematous-hemorrhagic changes, at 38-40 weeks gestation and in newborns on days 1-7 edematous-hemorrhagic and atelectatic changes, and on days 8-28 of gestation edematous-hemorrhagic changes. Relevance: Pneumopathy occupies a special place among respiratory diseases of newborns [1, 2, 6]. UNICEF studies have noted that pneumopathies cause stillbirths and death of newborns with disabilities in many countries of the world [3, 4, 5]. The aim and objectives of the study are to study the pathomorphological changes in various forms of pneumopathies in fetuses and newborns of different gestational ages. Materials and methods - The study studied the alveolar structures of the lungs of fetuses and newborns who died of pneumopathies in maternity hospitals of Andijan region in 2020-2024. Research results: At 18-22 weeks, the formation of 3rd-order respiratory bronchioles, alveolar clefts, and sacs, the alveolar appearance of 3rd-order bronchioles, and the formation of fetal arteries were observed.
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