INHIBIN A AS A PREDICTOR OF RECURRENT PREGNANCY LOSS IN WOMEN WITH HYPERPROLACTINEMIA

Received: 2025-04-14 19:06:17

Published: 2025-04-16

Abstract

Background. Recurrent pregnancy loss (RPL) remains a significant challenge in obstetric practice, impacting the physical and psychological well-being of affected women. Hyperprolactinemia, a common endocrine disorder among women of reproductive age, is associated with an increased risk of early pregnancy loss. Research Objective. To evaluate inhibin A as a biomarker for predicting recurrent pregnancy loss in women suffering from hyperprolactinemia and to highlight its diagnostic significance in early gestation. The article presents a comprehensive review of clinical and experimental findings related to inhibin A secretion dynamics, its role in endocrine regulation, and its diagnostic relevance in early pregnancy complications. The relationship between hyperprolactinemia and impairments in endometrial receptivity, luteal phase function, and hormonal support of early pregnancy is discussed in detail. Additionally, comparative analyses of inhibin A levels in normal versus complicated pregnancies are examined, with attention to its fluctuations across gestational trimesters.

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About the Authors

Mukhammedaminova Diyora Timurovna
Nasirova Khurshidakhon Kudratullaevna
Mirzaeva Umida Zakhidovna
Tashkent Pediatric Medical Institute
Maksudova Dilafruzkhon Ravshanovna

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How to Cite

1.
INHIBIN A AS A PREDICTOR OF RECURRENT PREGNANCY LOSS IN WOMEN WITH HYPERPROLACTINEMIA. MSU [Internet]. 2025 Apr. 16 [cited 2026 Mar. 2];(2):149-54. Available from: https://fdoctors.uz/index.php/journal/article/view/140

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