D VITAMINI METABOLIZISINING XUSUSIYATLARI VA UNING BOLALARDA METABOLIK SINDROM RIVOJLANISHDA TUTGAN O`RNI
Abstrakt
Mazkur maqolada ortiqcha vazni bor va semiz bolalar va o'smirlarda metabolik sindromning shakllanishida D vitaminining rolini aniqlash metabolik holat va xolekalsiferol kontsentratsiyasini o'rganish natijalari keltirilgan. O‘rganish natijalari birlamchi zveno, y'ani markaziy tuman poliklinikalari umumiy amaliyot shifokorlarining amaliy faoliyatiga keng joriy etish uchun tavsiya etiladi. Tadqiqot maqsadi: bolalar va o'smirlarda metabolik sindromning shakllanishida D vitaminining rolini aniqlash bilan, ortiqcha vazn va semirib ketgan bolalar va o'smirlarda metabolizm holati va xolekalsiferol kontsentratsiyasini aniqlash. Materiallar va usullar: semizlikning ekzogen-konstitutsiyaviy turi bo'lgan 106 nafar bolalar va o'smirlar, shuningdek, normal tana vazniga ega 30 nafar bolalar va o'smirlar tekshirildi. Uglevodlar va lipidlar almashinuvi, shuningdek, D vitamini darajasini aniqlash uchun antropometrik, klinik, biokimyoviy va ferment immunoassay tadqiqotlari kompleksi o'tkazildi. Tadqiqot natijalari: ortiqcha vaznli va semirib ketgan bolalar va o'smirlarda uglevod almashinuvi patologiyasi 47,6% hollarda, lipidlar almashinuvi muvozanati - 38,6%, qon zardobida xolekalsiferol etishmovchiligi - 76,9% hollarda sodir bo'lishi aniqlandi. Natijalar abdominal semirish belgilari bo'lgan bolalarning 58,4 foizida metabolik sindrom mavjudligini aniqlashga imkon berdi, uning to'liq versiyasi esa 20,9 foizni tashkil etdi. Metabolik sindromi bo'lgan bolalarda D vitaminining eng katta etishmasligi aniqlangan. Xulosa: qon zardobidagi xolekalsiferol metabolik jarayonlarning dastlabki nomutanosibligi uchun xavf omili bo'lib, keyinchalik metabolik sindromning simptomlar majmuasini hosil qiladi.
Nashr sanasi
Mualliflar haqida
Adabiyotlar ro'yxati
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