TROMBOTSITLARGA BOY, PLAZMA (TBP): RIVOJLANMAGAN HOMILADORLIKDAN KEYIN, REPRODUKTIV SALOMATLIGI BUZILGAN AYOLLARDA FOYDALANISH
Abstrakt
Ushbu tadqiqotda biz trombotsitlarga boy plazma bilan endometriy tiklashning yangi usulini qo'lladik va plazmaning endometriyga ta'sirini isbotladik. Tadqiqotning maqsadi: trombotsitlarga boy plazma (TBP)ning endometriy bo'yicha samaradorligini baholashdan iborat. Tadqiqot usullari: klinik-anamnestik, klinik-laboratoriya, Doppler yordamida ultratovush, fermentlarga bog'liq immunosorbent tahlil va statistik ma'lumotlarni o'z ichiga olgan. Tadqiqot natijalari: rivojlanmagan xomiladorlik tarixiga ega bo'lgan jami 80 ayol tekshirildi va bo'lajak o'rganildi, ular ikkita quyi guruhga bo'lindi: IA – oldindan tashxis qo'yish bo'yicha plazma terapiyasi bilan murakkab davolangan 40 nafar bemor, ushbu guruhda homiladorlikka chalingan 33 nafar bemor 22 haftagacha klinik kuzatuvdan o'tgan; Ib - standart terapiya olgan 40 nafar bemor. Boshqaruv guruhi ogʻrigan tugʻruq tarixisiz 22 haftagacha boʻlgan 50 nafar sogʻlom homilador ayoldan iborat edi - homilador boʻlish tarixi yoʻq edi. Xulosalar: Shunday qilib, murakkab davolashdan so'ng, shu jumladan ter terapiyasidan so'ng, bachadon bo'ynining tomir daraxtining barcha darajalarida gemodinamikaning tiklanishi kuzatildi. Asosiy ustunlik 82,5% hollarda homiladorlikning boshlanishi va qulayligi bilan isbotlangan.
Mualliflar haqida
Adabiyotlar ro'yxati
Julkunen M, Wahlstrom T, Seppälä M. Human fallopian tube contains placental protein 14. American Journal of Obstetrics and Gynecology. 1986;154(5):1076-1079;
Du J. et al. Efficacy and safety of platelet-rich plasma for the treatment of thin endometrium: a protocol for systematic review and meta-analysis //Medicine. – 2020. – Т. 99. – №. 3
Сулаева О.И. Получение богатой тромбоцитами плазмы:мифы и реальность// ISSN 2079-8334. Світ медицини та біології. 2017. № 3(61), стр.150-153. DOI 10.26724 / 2079-8334-2017-3-61-150-153
. Пальцев М.А., Кветной И.М. Руководство по нейроиммуноэндокринологии. — 2 е изд. — М.: Медицина, 2008. — 512 с
Achache H., Revel A. Endometrial receptivity markers, the journey to successful embryo implantation // Hum. Reprod. Update. — 2006. — Vol. 12, N 6. — P. 731–746;
Elevated soluble Fas ligand levels may suggest a role for apoptosis in women with endometriosis / Garcia-Velasco J.A. // J. Fertil. Steril. — 2002. — Vol. 78. — P. 855–859.
Добродицкая А. Д. и др. КЛИНИЧЕСКОЕ ЗНАЧЕНИЕ ВЫЯВЛЕНИЯ ТРОМБОФИЛИИ У БЕРЕМЕННЫХ С ОТЯГОЩЕННЫМ АКУШЕРСКИМ АНАМНЕЗОМ С ЦЕЛЬЮ ПРОФИЛАКТИКИ АНТЕНАТАЛЬНОЙ ГИБЕЛИ ПЛОДА //Клинические и медико-организационные решения по сохранению репродуктивного здоровья семьи. – 2017. – С. 77-80;
Maleki-Hajiagha A. et al. Intrauterine infusion of autologous platelet-rich plasma in women undergoing assisted reproduction: A systematic review and meta-analysis //Journal of reproductive immunology. – 2020. – Т. 137. – С. 103078.
. Sharara F. I. et al. A narrative review of platelet-rich plasma (PRP) in reproductive medicine //Journal of Assisted Reproduction and Genetics. – 2021. – Т. 38. – С. 1003-1012;
Aghajanova L., Cedars M. I., Huddleston H. G. Platelet-rich plasma in the management of Asherman syndrome: case report //Journal of assisted reproduction and genetics. – 2018. – Т. 35. – С. 771-775
Du J. et al. Efficacy and safety of platelet-rich plasma for the treatment of thin endometrium: a protocol for systematic review and meta-analysis //Medicine. – 2020. – Т. 99. – №. 3
Mouanness M. et al. Use of intra-uterine injection of platelet-rich plasma (PRP) for endometrial receptivity and thickness: a literature review of the mechanisms of action //Reproductive Sciences. – 2021. – Т. 28. – С. 1659-1670.
Tang R. et al. Clinical evaluation of autologous platelet-rich plasma therapy for intrauterine adhesions: a systematic review and meta-analysis //Frontiers in Endocrinology. – 2023. – Т. 14
Soliman A. et al. How autologous platelet-rich plasma affects pregnancy and birth outcomes in women with repeated embryo implantation failure: A prisma-compliant meta-analysis //Turkish Journal of Obstetrics and Gynecology. – 2023. – Т. 20. – №. 2. – С. 154
Liu K. et al. Autologous platelet‐rich plasma intrauterine perfusion to improve pregnancy outcomes after implantation failure: A systematic review and meta‐analysis //Journal of Obstetrics and Gynaecology Research. – 2022. – Т. 48. – №. 12. – С. 3137-3151;
Maged A. M. et al. The value of platelet-rich plasma in women with previous implantation failure: A systematic review and meta-analysis //Journal of Assisted Reproduction and Genetics. – 2023. – Т. 40. – №. 5. – С. 969-983;
Jin X. H., Li Y., Li D. Intrauterine interventions for women with two or more implantation failures: A systematic review and network meta-analysis //Frontiers in Endocrinology. – 2022. – Т. 13. – С. 959121
Носкова И. Н., Артымук Н. В. Эффективность преконцепционной интравагинальной пелоидотерапии у женщин с потерей беременности в ранние сроки // Мать и дитя в Кузбассе. 2012. № Спецвыпуск 1. С. 113-118. URL: https://cyberleninka.ru/article/n/effektivnost-prekontseptsionnoy-intravaginalnoy-peloidoterapii-u-zhenschin-s-poterey-beremennosti-v-rannie-sroki
Нигаметзянова Г. Р. Неразвивающаяся беременность // Лечение и профилактика. 2017. № 2. С. 47-55. URL: https://readera.org/nerazvivajushhajasja-beremennost-143162918;