YALLIG‘LANISHGA QARSHI DORI VOSITALARI POLIPRAGMAZIYASIDA JIGAR PARENXIMASINING MORFOMETRIK O‘ZGARISHLARINI O‘RGANISH

Usanov Sanjar Sadinovich
Abduraimov Zafarjon Abduraimovich
Nashr sanasi https://doi.org/10.56121/2181-3612-2024-1-13-17
TO'LIQ MATN:

Abstrakt

Maqsad. Yallig‘lanishga qarshi dori vositalari polipragmazisida oq kalamushlarning jigari tuzilishidagi morfometrik o‘zgarishlarni o‘rganish.


Material va Metodlar: Tadqiqot 210 dan 320 g gacha bo‘lgan og‘irlikdagi 50 ta erkak oq kalamushlarda o‘tkazildi, ular standart dietaga muofiq, suvga iste'moli erkin va normal yoritish rejimiga ega vivariumda saqlandi. Hayvonlar 3 guruhga bo‘lindi.


Natijalar: 3-guruhdagi kalamushlarning morfometrik parametrlarini 2-guruhdagi kalamushlar ko‘rsatgichlari bilan solishtirganda sezilarli pasayish aniqlandi. Jigar hujayralari maydoni 5,14%, 5,05%, 3,19% va 3,02% ga, markaziy vena diametri 8,13%, 6,11%, 4,08% va 3,42% ga kamaydi, o‘t yo‘llari bo‘shlig‘i diametri 6,33%, 5,09%, 3,12% va 3,08% ga kamaydi, arteriya qon tomirlari diametri 7,12%, 5,07%, 5,03% va 4,48% ga kamaydi, distal jigar o‘t yo‘llari bo‘shlig‘i diametri 4,47%, 4,04%, 3,07% va 2,31% ga kamaydi.


Xulosa. Yallig‘lanishga qarshi dori vositalarining polipragmaziyasi jigarga salbiy ta'siri mavjud, bunda o‘t chiqarishga zararli ta'sirini ko‘rsatadi, o‘t chiqarishni kamaytiradi va organizm uchun yetarli darajada xavf tug‘diradi.

Nashr sanasi

Mualliflar haqida

Usanov Sanjar Sadinovich
Samarqand davlat tibbiyot universiteti
Abduraimov Zafarjon Abduraimovich
Samarqand davlat tibbiyot universiteti

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