OPTIMIZATION OF NEPHROGENIC SEPSIS REHABILITATION IN CHILDREN

FULL TEXT:

Abstract

Relevance. This retrospective study involved the examination of 34 children aged 7 to 14 years suffering from nephrogenic sepsis. Detailed anamnesis data were collected, including physical development indicators, general and biochemical blood tests, urinalysis, and stool analysis. Aim of the study. The primary objective was to assess the clinical effectiveness of comprehensive therapy using the drug Nefroton Kids in combating infections caused by the most common pathogens of sepsis in children. Materials and methods of the study. The treatment protocol included the use of Nefroton Kids as part of combination therapy for managing infections such as Escherichia coli (E. coli) (responsible for approximately 60–80% of cases), Klebsiella spp., Proteus mirabilis, Staphylococcus saprophyticus, Enterococcus faecalis, and Pseudomonas aeruginosa. Results. Clinical, laboratory, and instrumental data indicated an improvement in the patients' condition, with the recovery period reduced by 2–5 days. Conclusion. Thus, the use of Nefroton Kids appears to be effective not only in the treatment of kidney pathologies but also in preventing complications arising after nephrogenic sepsis.

About the Authors

List of references

Gül, F., Arslantaş, M. K., Cinel, İ. & Kumar, A. Changing Definitions of Sepsis. Turkish J. Anaesthesiol. Reanim. 45, 129–138 (2017).

Prout, A.J.; Talisa, V.B.; Carcillo, J.A.; Mayr, F.B.; Angus, D.C.; Seymour, C.W.; Chang, C.H.; Yende, S. Children with chronic disease bear the highest burden of pediatric sepsis. J. Pediatr. 2018, 199, 194–199.

Fleischmann-Struzek, C.; Goldfarb, D.M.; Schlattmann, P.; Schlapbach, L.J.; Reinhart, K.; Kissoon, N. The global burden of paediatric and neonatal sepsis: A systematic review. Lancet Respir. Med. 2018, 6, 223–230.

Stoll BJ, Hansen NI, Sánchez PJ, et al. Early onset neonatal sepsis: the burden of group B streptococcal and E. coli disease continues. Pediatrics. 2011; 127(5):817–826.

World Health Organization Managing possible serious bacterial infection in young infants when referral is not possible; 2015. Available from: http://www.who.int/maternal_child_adolescent/documents/bacterial-infection-infants/en/

How to Cite

1.
Karimdjanov I, Dinmukhamadieva D, Xoltayeva F, Tursunbayev A. OPTIMIZATION OF NEPHROGENIC SEPSIS REHABILITATION IN CHILDREN. MSU [Internet]. 2025 Apr. 16 [cited 2025 Apr. 20];(2):161-3. Available from: https://fdoctors.uz/index.php/journal/article/view/142
Views: 5

Most read articles by the same author(s)