NECROTIC ENTEROCOLITIS OF NEWBORNS (literature review)
Abstract
Necrotizing enterocolitis (NEC) is a neonatal inflammatory bowel disease and is one of the most threatening disease in neonatal gastroenterology. The average incidence of necrotizing enterocolitis 2,4:1000 infants (1 to 10:1000), or about 2.1% (from 1 to 7%) of the total number of children entering the neonatal intensive care unit. The incidence of disease increases with decreasing gestational age at birth. The share of full-term infants accounts for 10-20% of cases of NEC. In recent years, necrotic enterocolitis has remained one of the leading causes of morbidity and mortality among premature infants with low body weight. The active study of the most important diagnostic factors in the early stages of the disease, which is difficult to diagnose, the choice of a treatment method is one of the first tasks of neonatologists and surgeons of the children's department.
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List of references
Boronina I. Dynamics of survival of children with very low and extremely low birth weight in the Voronezh region from 2000 to 2012 // Journal of Russian Perinatology and Pediatrics, 2015. 1 . pp. 27-32
Bryksina E.Yu. et al. Functional pathology of the upper gastrointestinal tract in premature infants: pathogenetic aspects of the development of micro aspiration of gastric contents // Bulletin of RUDN, Medicine series, 2015, no. 3, pp. 107-114).
Diseases of the stomach and duodenum in children / edited by: S. V. Belmer, A. Yu. Razumovsky, A. I. Khavkin. - Moscow: Medical practice, 2017 - 536 p.Neonatology: A Practical Approach to Neonatal Diseases. Eds. Buonocore G., Bracci R., Weindling /M. Italia: Springer-Verlag; 2018; 1348.
Wendy H.Y., Amuchou S.S., Vibhuti S.S. et al. Incidence and timing of presentation of necrotizing enterocolitis in preterm infants. // Pediatrics. 2019; 129:298-304.
Neu, J. Necrotizing Enterocolitis: The Future. Neonatology, 2020; 117(2), 240–244.
Taufik, M. L., & Lestari, D. Diagnosis dan Tatalaksana Enterokolitis Nekrotikans. Cermin Dunia Kedokteran, 2021; 48(4), 225-230.
Ou, J., Courtney, C. M., Steinberger, A. E., Tecos, M. E., & Warner, B. W. 2020. Nutrition in necrotizing enterocolitis and following intestinal resection. Nutrients, 12 (2), 1-16
Doheny, K. K., & Travagli, R. A. Necrotizing enterocolitis: It’s not all in the gut. Experimental Biology and Medicine, 2020; 245(2), 85-95
Frost BL, Modi BP, Jaksic T, Caplan MS. New medical and surgical insightsinto neonatal necrotizing enterocolitis: A review. JAMA Pediatrics.2017; 171(1): 83-88
Denning TL, Bhatia AM, Kane AF, et al. Pathogenesis of NEC: Role of theinnate and adaptive immune response. Seminars in Perinatology. 2017; 41:15-28.