THE ROLE OF EMBRIOGENETIC FAKTORS IN THE TEROTEGENESIS OF ANORECTAL MALFORMATION

Authors

  • Yuldashеv Muzaffar Abduvaxobovich Andijan State Medical Institute
  • Toshboеv Shеrzod Olimovich Andijan State Medical Institute
  • Mirzakarimov Baxrom Xalimjonovich Andijan State Medical Institute

DOI:

https://doi.org/10.56121/2181-3612-2022-1-04-07

Keywords:

anorectal malformation, aetiology, embryology, cloaca, genetic factors

Abstract

Anorectal malformations (ARP) are congenital malformations that are common in pediatric surgery. Although surgi-cal procedures correct anatomical abnormalities, postoperative bowel function is not always satisfactory. The etiology of ARM remains unclear. In this review, summarize the current understanding of embryological and genetic factors contrib-uting to the pathogenesis of ARM, based on published animal models, human genetic studies, and epidemiological studies. Better understanding of these factors could help manage ARM better.

Author Biographies

Yuldashеv Muzaffar Abduvaxobovich, Andijan State Medical Institute

Assistent

Toshboеv Shеrzod Olimovich, Andijan State Medical Institute

Candidate of Medical Sciences, Associate Professor

Mirzakarimov Baxrom Xalimjonovich, Andijan State Medical Institute

Candidate of Medical Sciences, Associate Professor

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Published

2022-07-30

How to Cite

Yuldashеv M., Toshboеv S., and B. Mirzakarimov. “THE ROLE OF EMBRIOGENETIC FAKTORS IN THE TEROTEGENESIS OF ANORECTAL MALFORMATION”. Medical Science of Uzbekistan, no. 1, July 2022, pp. 04-07, doi:10.56121/2181-3612-2022-1-04-07.

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Section

Articles