Jild 5 № 3 (2026): May-Iyun
2026-06-29
Ochiq kirish

SURUNKALI PARODONTIT VA HAMROH OSHQOZON-ICHAK TRAKTI PATOLOGIYASI BO‘LGAN BEMORLARDA KOMPLEKS PATOGENETIK DAVOLASHDAN KEYINGI KLINIK PARODONTOLOGIK KO‘RSATKICHLAR VA ULARNING DINAMIKASI

Mukhlisa A.Saidova
Xaydar P.Kamilov
https://doi.org/10.56121/MSU-2026-3-00017

Qabul qilingan: 2026-03-24

Nashr etilgan: 2026-06-29

PDF (ruscha)
Crossmark Crossmark

Annotatsiya

Maqsad. Surunkali parodontit (SP) oshqozon-ichak trakti (OIT) kasalliklari bilan birga kechgan bemorlarda kompleks patogenetik davolashdan keyingi boshlang‘ich klinik parodontologik ko‘rsatkichlar va ularning dinamikasini izolyatsiyalangan SP bilan taqqoslab baholash.


Materiallar va usullar. Tadqiqotga jami 245 nafar ishtirokchi jalb qilindi: SP bilan kasallangan 205 bemor (asosiy guruh, n = 107 — SP+OIT; taqqoslash guruhi, n = 98 — izolyatsiyalangan SP) va 40 nafar sog‘lom shaxs (nazorat guruhi). PPD, CAL, GBI, BOP va OHI-S ko‘rsatkichlari T0, T1 (30 kun) va T2 (90 kun) vaqt nuqtalarida baholandi.


Natijalar. Boshlang‘ich PPD va CAL ko‘rsatkichlari asosiy guruhda taqqoslash guruhiga nisbatan statistik jihatdan sezilarli darajada yuqori bo‘lgan (p < 0,05). 90-kunga kelib kompleks davolash (VLT + Nigella sativa moyi) PPD ko‘rsatkichini 2,6 ± 0,4 mm gacha va GBI ko‘rsatkichini 18,7 ± 4,1% gacha kamaytirgan, taqqoslash guruhida esa ushbu ko‘rsatkichlar mos ravishda 2,9 ± 0,4 mm va 28,3 ± 4,8% ni tashkil etgan (p < 0,05).


Xulosa. VLT va Nigella sativa moyi qo‘llanilgan kompleks davolash klinik parodontologik ko‘rsatkichlarning yanada yaqqol yaxshilanishi bilan bog‘liq bo‘lgan. Ushbu yondashuvning mustaqil klinik ustunligini tasdiqlash uchun klinik jihatdan bir xil guruhlarda randomizatsiyalangan qiyosiy tadqiqotlar o‘tkazilishi zarur.

Kalit so‘zlar

Adabiyotlar ro'yxati

  1. Tonetti, M.S.; et al. Impact of the global burden of periodontal diseases on health, nutrition and wellbeing of mankind: a call for global action. J. Clin. Periodontol. 2023, 50(4), 372–378. https://doi.org/10.1111/ jcpe.13760.

  2. Papapanou, P.N.; et al. Periodontitis: Consensus report of workgroup 2 of the 2017 World Workshop on the Classification of Periodontal and Peri-Implant Diseases. J. Clin. Periodontol. 2018, 45(Suppl. 20), S162–S170. https://doi.org/10.1111/jcpe.12946.

  3. Sanz, M.; et al. Periodontitis and cardiovascular diseases: Consensus report. J. Clin. Periodontol. 2020, 47(3), 268–288. https://doi.org/10.1111/jcpe.13189.

  4. Bulgakova, A.I.; et al. Periodontal and GI comorbidity: microcirculatory correlates. Stomatologiya 2022, 101(3), 12–18. (In Russ.).

  5. Камилов, Х.П.; Саидова, М.А. Влияние патологии ЖКТ на патогенез воспалительных заболеваний пародонта. Интегративная стоматология и ЧЛХ 2025, 4(3), 121–127.

  6. Саидова, М.А.; Камилов, Х.П. Цитокиновый профиль и уровень sIgA у пациентов с хроническим пародонтитом и сопутствующей патологией ЖКТ. Медицинская наука Узбекистана 2024, (3), 41–48.

  7. Саидова, М.А.; Камилов, Х.П. Состояние микроциркуляции тканей пародонта по данным ЛДФ у пациентов с ХП и патологией ЖКТ. Медицинская наука Узбекистана 2025, (1), 31–39.

  8. Tonetti, M.S.; Greenwell, H.; Kornman, K.S. Staging and grading of periodontitis: Framework and proposal of a new classification and case definition. J. Clin. Periodontol. 2018, 45(Suppl. 20), S149–S161. https://doi.org/10.1111/jcpe.12945.

  9. Hajishengallis, G.; Chavakis, T. Local and systemic mechanisms linking periodontal disease and inflammatory comorbidities. Nat. Rev. Immunol. 2021, 21(7), 426–440.

  10. Graziani, F.; et al. Efficacy of periodontal treatment in patients with periodontitis and systemic comorbidities: a systematic review. J. Clin. Periodontol. 2022, 49(Suppl. 24), 142–166.

  11. Kırzıog˘ lu, F.Y.; et al. Vacuum-laser therapy for periodontal regeneration: a randomized controlled trial. Photobiomodul. Photomed. Laser Surg. 2021, 39(4), 261–269.

  12. Ahmad, M.F. Nigella sativa and thymoquinone in oral and periodontal health: a review. J. Tradit. Complement. Med. 2021, 11(5), 391–399.

  13. Herrera, D.; et al. Treatment of stage I–III periodontitis — The EFP S3 level clinical practice guideline. J. Clin. Periodontol. 2022, 49(Suppl. 24), 4–60. https://doi.org/10.1111/jcpe.13639.

  14. Bertl, K.; et al. Laser Doppler flowmetry in periodontology: a systematic review. J. Clin. Periodontol. 2022, 49(4), 339–352. https://doi.org/10.1111/jcpe.13578.

  15. Faure, M.; et al. Microcirculatory assessment in periodontal treatment monitoring: a prospective study. Clin. Oral Investig. 2023, 27(5), 2311–2320.

Mualliflar haqida

Mukhlisa A.Saidova
Mukhlisa_saidova95@mail.ru
Tashkent State Medical University
Xaydar P.Kamilov
Mukhlisa_saidova95@mail.ru
Tashkent State Medical University

Litsenziya

Creative Commons License

This work is licensed under a Creative Commons Attribution 4.0 International License.

Qanday iqtibos keltirish kerak

1.
SURUNKALI PARODONTIT VA HAMROH OSHQOZON-ICHAK TRAKTI PATOLOGIYASI BO‘LGAN BEMORLARDA KOMPLEKS PATOGENETIK DAVOLASHDAN KEYINGI KLINIK PARODONTOLOGIK KO‘RSATKICHLAR VA ULARNING DINAMIKASI. MSU [Internet]. 2026 Jun. 29 [cited 2026 Sep. 29];5(3). Available from: https://fdoctors.uz/index.php/journal/article/view/285
Crossref
Scopus
Google Scholar
Europe PMC

O'xshash maqolalar

Siz ham ushbu maqola uchun {$ advancedSearchLink} olishingiz mumkin.

Xuddi shu muallif (lar) ning eng ko'p o'qilgan maqolalari


ISSN 2181-3612 (Online)