REVMATOID ARTRIT RIVOJLANISHINING TURLI BOSQICHLARIDA KASALLIK KLINIK KECHISH XUSUSIYATLARI
Abstrakt
Mavzuning dolzarbligi. Revmatoid artritda (RA) kasallik prognozning sezilarli yaxshilanishiga olib keluvchi tashxislash va davolashda katta yutuqlarga erishilganiga qaramay, ushbu patologiyaning asosiy tibbiy muammolari – bemor hayot sifatini tiklash va o'limni populyatsiya darajasida kamaytirish – hal qilinishi qiyind vazifa bo`lib qolmoqda. Tadqiqotning maqsadi RAning erta va rivojlangan bosqichida kasallikning klinik va funktsional parametrlari (DAS28, VASH, FS) xususiyatlarini o'rganish edi. Tadqiqot materiallari va usullari. Tadqiqotga RA bilan og'rigan 103 bemorlarda, DAS28 indeksi bo'yicha kasallik faolligi, zararlangan bo'g'imlarda og`riq darajasini VASH shkalasi bo`yicha va bo'g'imlarning funktsional buzilishi (BFB) darajasi baholadi. Tadqiqot natijalari. Tadqiqotlar shuni ko'rsatdiki, I guruh bemorlari II guruh bemorlariga (p<0,001) nisbatan BFB og'irroq namoyon bo`ldi. VASH shkalasi bo'yicha og'riq intensivligi II guruhga nisbatan I guruh bemorlarida 20% yuqori bo'lgan (p<0,001). DAS28 bo'yicha kasallik faolligi I guruh bemorlarida II guruhga nisbatan yuqori bo'lgan (p<0,01). Xulosa. Shunday qilib, kasallikning asosiy klinik ko'rsatkichlarini tahlil qilish, RA erta bosqichlariga qaraganda, rivojlangan RAda yanada og'ir va uzoq davom etishini aniq ko'rsatdi.
Nashr sanasi
Mualliflar haqida
Adabiyotlar ro'yxati
Aletaha D, Smolen JS. Diagnosis and Management of Rheumatoid Arthritis: A Review. JAMA. 2018;320(13):1360–1372. doi:10.1001/jama.2018.13103
Iskandarov FI SIGNIFICANCE OF EARLY DIAGNOSTIC CRITERIA IN RHEUMATOID ARTHRITIS AND UNDIFFERENTIATED ARTHRITIS // Journal of Humanities and Natural Sciences. – 2024. – No. 9. – P. 188-193.
Karateev Dmitry Evgenievich, Olyunin Yu. A., Luchikhina E. L. New classification criteria for rheumatoid arthritis ACR/EULAR 2010: a step forward to early diagnosis // Scientific and practical rheumatology. 2011. No. 1.
Nasonov E. L. Problems of immunopathology of rheumatoid arthritis: evolution of the disease. Scientific and practical rheumatology. 2017; 55 (3): 277-294.
Olyunin Yu. A. Pain assessment in rheumatoid arthritis. Practical significance. Modern rheumatology. 2019;13(1):121-8
Shodikulova G. Z., Babamuradova Z. B., Iskandarov F. I. Pathogenetic significance of cytokine imbalance in the study of the development and course of undifferentiated arthritis at the stages of rheumatoid arthritis // Research Journal of Trauma and Disability Studies. - 2024. - Vol. 3. - P. 2.
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